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In the SURMOUNT clinical trial, tirzepatide produced greater average weight loss (up to 22.5% of body weight) compared to semaglutide (up to 17.5% at the highest tested dose)

However, clinical evidence and patient experiences point to two main mechanisms that likely contribute to feeling more tired than usual while taking Wegovy: What many patients dont realise is that the dramatic appetite reduction from Wegovy can lead to consuming fewer calories than their body needs for normal energy levels

The five most common mistakes Mistake one: using a chart for the wrong concentration

They may reduce your dose, extend the time at the current level, or prescribe supportive medications like ondansetron for nausea management