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Zhong P, Peng J, Hu Y, Zhang J, Shen C

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Moderate: Widespread flushing, swelling, and mild airway tightening

In summary, the physiological function of multisite phosphorylation is considered to be as follows: under conditions of high Met concentration, it provides maximum inhibition of MTHFR by SAM, so that one-carbon units are spared for key processes, such as purine and deoxythymidine monophosphate (dTMP) synthesis