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Marchesi, J

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Single-agonist compounds such as Semaglutide, discussed extensively in our companion article on GLP-1 agonists and tissue laxity, act on a single receptor pathway and are typically studied for broad appetite suppression and total weight-reduction effects rather than VAT-specific outcomes

The hydrogen bonding with chain A at Gly-121 on the backbone of TNF- allowed for docking, and the sugar molecule also demonstrated hydrogen bonding with chain A at Tyr-59