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Although Grx are mainly responsible for deglutathionylation reactions, recent evidence has indicated a role for Grx in protein glutathionylation, mediated by the stabilization of a GSH thiyl radical which is then subsequently transferred to an available protein thiol (Starke et al., 2003)

Hackney A.C

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Although the mechanisms of ferroptosis have been well studied, the possible molecular and pathogenic mechanisms involved in CNS trauma remain unclear, indicating that the elucidation of the mechanisms of ferroptosis is important