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In terms of mechanisms, tesofensine inhibits the uptake of serotonin, noradrenaline, and dopamine, leading to appetite suppression and increased feelings of fullness

The manufacturer of Ozempic and Wegovy, Novo Nordisk, states that semaglutide reaches a steady level in the bloodstream after about 4-5 weeks of use, so you might notice a change in appetite by then

Wait for the dose counter to reach 0 mg, and then slowly count to six before removing the needle from your skin

Even though GLP-1 RAs mimic a natural hormone in the body, they do have some potential GI side effects, including constipation, which appears to be more common than diarrhea in patients who reach out to Oshi Health for help