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Screening for Rho-kinase 2 inhibitory potential of Indian medicinal plants used in management of erectile dysfunction

L-arginine is necessary for achieving and maintaining an erection due to its effect on nitric oxide in the nerves

[2] Sies H et al

The constant levels of marker proteins such as GAPDH, combined with observations indicating that knockdown of the UPR element, BiP/Grp78 , revealed no detectable effects on Nrf2, GCLC, or glutathione, further support the conclusion that NFT-mediated stabilization of Nrf2 is a major contributor to its accumulation and the subsequent stimulation of GCL and glutathione synthesis