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It is not widely utilized and therefore data is still limited

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As demonstrated in xenograft mouse models, exposure of the nanoparticle to an external electric field at cancerous tissues resulted in a thermally activated retro-Diels-Alder reaction at the linker and release of the anticancer drug (Figure 117B)

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It also triggers immune responses when eDNA interacts with host immune cells, but the ultimate effect of such immunity is anti-inflammatory, which is not conducive to biofilm clearance, instead leading to refractory and chronic infections

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