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The funnel plots were performed to check a part of the reporting bias and a part of the heterogeneity, and there were low risk of the reporting bias and no issues with heterogeneity

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In this study, we developed a RiPPs-based approach for the biosynthesis of tirzepatide and its variants in E

We defined the PZ as distal to the first row of cells, where at least two distinctive crescent-shaped germ nuclei were present 73 and obtained the total number of PZ spheres