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Section 1848(e)(6)(B) of the Act specified that the GPCI values used for payment in a transition area are to be phased in over 6 years, from 2017 through 2022, using a weighted sum of the GPCIs calculated under the new MSA-based locality structure and the GPCIs calculated under the PFS locality structure that was in place prior to CY 2017

It is readily used by the body for antioxidant protection and detoxification

It was developed to specifically target fat metabolism, aiming to promote fat breakdown and reduce new fat formation, without stimulating growth or affecting IGF-1 levels, which are associated with full-length growth hormone