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Further work aimed at developing longitudinal-based studies to assess whether there may be a bidirectional relationship between UPF and mental health disorders offers a new avenue for further translational research studies
32 Behavioral assessments confirmed the development of PTSD-like symptoms, with mice exhibiting impaired fear extinction and retrieval in the contextual fear conditioning (CFC), as indicated by increased freezing behavior during retrieval sessions compared to controls (Fig
Further phase 3 clinical trials with larger sample sizes are needed to thoroughly assess the immunopathological effects of MMP inhibitors like doxycycline on TB
It generates reactive oxygen species (ROS) that trigger the dysregulation of essential cellular functions, ultimately affecting cellular health and homeostasis
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