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Skipping doses can lead to increased hunger and cravings , making it harder to stay on track with your goals

Avoid high-intensity exercise during an active headache as it increases blood pressure and can worsen the pain

Most patients find these symptoms manageable with dietary adjustments, increased water intake, and slower dose progression

This dissociation suggests that tolerability may depend not solely on total weight loss or dose intensity, but on mechanistic distinctions between dual incretin agonism and GLP-1only therapy