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In this review, we will focus on the study of cardiovascular, musculoskeletal, and hepatic comorbidities in the four most used and induced RA models: collagen-induced arthritis (CIA), adjuvant-induced arthritis (AIA), pristane-induced arthritis (PIA), and serum transfer K/BxN
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As illustrated in Figure 1, this review comprehensively analyzes the mechanistic basis of GLP-1RAs in ocular diseases, synthesizes emerging clinical and preclinical evidence, and underscores their potential to redefine therapeutic strategies for vision-threatening disorders through multi-targeted disease modification
783 Mechanically, HUC-MSCs-derived exosomes inhibit ferroptosis by delivering circBBS2, which sponges miR-494 and enhances SLC7A11 levels, thereby inhibiting ferroptosis and alleviating ischemic stroke
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