gip/glp-1 The activity of GLP-1 and GIP for Type 2 Diabetes and Obesity 🔗 https://bit.ly/4p18nLz Curious how GLP-1

Given the differences in the MedDRAs categorization rules, some potential PTs that were not included may exist, e.g., depression suicidal (belonging to HLGT level, depressed mood disorders and disturbances) and intentional overdose (belonging to HLGT level, overdoses, and underdoses NEC)

And then typically there's an increase that'll happen like around a month, but there doesn't have to be

The ACHIEVE-3 head-to-head trial showed slightly higher discontinuation with orforglipron than with oral semaglutide, consistent with orforglipron's greater potency and attendant greater GI activation

Compounded drugs can be important for overcoming shortages or meeting unique patient needs but compounders should not try to compound drugs in a way that circumvents FDAs approval process. The 30 companies that received warning letters are mostly small to midsize, digital telehealth providers that moved quickly to meet surging consumer demand for GLP-1 weight loss therapies when manufacturing capacity constraints limited supplies