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Scientific studies conducted in different research laboratories around the world have established that human tri-peptide GHK-Cu possesses a plethora of biological actions including activation of wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth

Deletion of tnaA and sdaA (ZJ012) resulted in 13.10 and 16.70 % increases in the GSH concentration and yield compared with ZJ000, respectively

Notably, it has been reported that the gut microbes could metabolise tryptophan into tryptamine, kynurenine and indole derivatives involving the indoleamine 2,3-dioxygenase 1 (IDO1) and aryl hydrocarbon receptor (AHR) that have crucial roles in the immune homeostasis and tumour immune microenvironment respectively [247,248,249,250,251]