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Petrie M, Borlaug B, Buchholtz K et al (2024) HERMES: effects of ziltivekimab versus placebo on morbidity and mortality in patients with heart failure with mildly reduced or preserved ejection fraction and systemic inflammation

Reported benefits (per available research): Studied for its ability to produce sustained, dose-dependent increases in growth hormone and IGF-1 secretion in a Phase 1 human trial in healthy adults, published by Teichman et al

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Excessive consumption of coffee other than tea, insufficient water consumption, excessive salt consumption, excessive intake of oxalate-rich vegetables and animal protein are factors that increase the risk