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Sudden glucose spikes can trigger cravings and overeating, creating a cycle that promotes weight gain

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In sheer numbers, that means that while 8,722 Americans in this age group took a GLP-1 in 2020, 60,567 were doing so by the end of 2023

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Figure 2 More recently, a multiple hits theory has been proposed, with the addition of other pathogenic factors in NAFLD development: low-grade chronic inflammation, genetic and epigenetic mutations, and intestinal microbiota

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