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Why the thigh is one of the best injection sites for tirzepatide Three sites are approved for subcutaneous tirzepatide injections: the abdomen, the front of the thigh, and the back of the upper arm

[7] It is advisable for patients to inform their healthcare provider of all medications and supplements they are taking, so that potential interactions can be monitored and managed appropriately

The GIP receptor activation component of tirzepatide may provide additional effects, as GIP receptors are expressed on immune cells and adipocytes, potentially modulating inflammatory responses in these tissues