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The FDA indication determines what a medication is approved to treat, even if weight loss shows up as a side effect in diabetes studies

[My recent post on this topic here.] (29:18): The ability to assess thousands of proteins in each individual, and it's giving us new insights about cause and effect as you alluded to, the relationship with as you said, MACE (major adverse cardiovascular events) and the actions of this drug class

doi: 10.1038/nrendo.2011.77

Notably, GLP-1 significantly suppressed plasma pancreatic polypeptide concentrations following the first meal,68 but this effect diminished substantially after the second test meal,72 suggesting autonomic nervous system adaptation to continuous GLP-1 administration