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Monitor patients response to treatment closely

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While the sulfamate modification overcomes the obstacle of poor water solubility common in natural phenolic complexes, hurdles remain for clinical translation, including the need to address challenges associated with clinical scalability, targeting efficacy and the potential for off-target effects such as neurotoxicity and myelosuppression typically associated with tubulin inhibitors (115)

no alcohol within 24 hours of flying), driving public or heavy vehicles, operating commercial ships or machinery