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Pfizer and Novo Nordisk engaged in a high-profile tussle over the acquisition of Metsera, an obesity and cardiometabolic clinical-stage biotech, highlighting the strategic value attributed to innovative pipelines in an increasingly crowded field

Protein glycation is thus responsible for the development of inflammation, but it also disrupts extracellular matrix remodeling and intercellular signaling 77,78

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When studies had multiple intervention arms, we treated each arm as a separate arm and divided the number in the comparator by the number of intervention arms to avoid duplicative counting.19 The models returned weekly estimates, which have been converted to monthly rates of regain for ease of interpretation