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The HPLC trace for GSH in the presence of complex 1 after 1, 3 and 5 min of plasma treatment showed one signal at 1.11 min, which is again assigned to the GSO 3 H molecule

Importantly, glutathione (GSH) acts as an essential cofactor for the enzyme family glutathione peroxidases (GPx), which catalyze the reduction of hydrogen peroxide and lipid hydroperoxides into water and their corresponding alcohols

have reported that metformin combined with probiotic-derived outer membrane vesicles can modulate the gut microbiota and eliminate excess reactive oxygen species (ROS) in a murine inflammatory bowel disease (IBD) model [18]