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In HIV-related research, daily tesamorelin reduced deep belly fat meaningfully versus placebo, but it works best for body composition, not big weight loss numbers

As you progress through higher doses, weight loss tends to accelerate and then stabilize around week 12 to 16

Patients who often respond best: Have insulin resistance or prediabetes Follow protein-focused nutrition Stay consistent with dosing Maintain hydration Combine medication with lifestyle support Medication is a tool but long-term success still depends on comprehensive care

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