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Conventional therapies like physical therapy, occupational therapy, and intravenous immunoglobulin remain important

Kidney disease or severe liver impairment can slow elimination, potentially requiring dose adjustmentsan important consideration for PlexusDx patients to discuss with their prescribing physician during initial consultation

Both alcohol and isoniazid induce CYP2E1 and affect APAP-induced ALI by increasing NAPQI, the hepatotoxic metabolite of APAP, indicating that CYP2E1 may be the major P450 contributing to conversion of APAP to NAPQI (Zand et al., 1993

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