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Also, hypomethylation of GRP78, FTO and TNF and PDGFR-, and hypermethylation of leptin, PPARG, LXR, Lipin 1 and GRP78 in mothers have been shown to predispose offspring to obesity, disruption of hepatic lipid metabolism and other cardiometabolic outcomes [164]

Ferroptosis is a targetable detrimental factor in metabolic dysfunction-associated steatotic liver disease