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MS: Conceptualization, Writing original draft, Writing review & editing, Data curation

Sangiorgi, S

We report that treatment with a safe and well-tolerated oral antioxidant compound, NAC, can effectively prevent a host of adolescent-THC-induced pathophenotypes

1 Introduction Chronic obstructive pulmonary disease (COPD) is a highly prevalent, progressive respiratory disorder characterized by persistent airway inflammation, irreversible airflow limitation, and alveolar destruction ( Emerging evidence now positions ferroptosis not merely as a consequence but as a key amplifier of COPD pathology, particularly through its dynamic interplay with immune dysregulation ( 2 Ferroptosis: a novel form of regulated cell death Ferroptosis is a distinctive type of regulated cell death that significantly differs from apoptosis, necrosis, and autophagy