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They showed better effects in improving mouse motor function scores, promoting the repair and regeneration of synapses or dopaminergic neurons (TH+, GDNF, synaptophysin), and inhibiting neuroinflammatory responses (IBA-1, IL-2) compared to liraglutide and DA-JC1, highlighting the advantage of targeting more sites

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These trials showcased its superior efficacy in glycemic control and weight management

What makes tirzepatide fundamentally different is that it doesnt just act on GLP-1it also targets GIP, a second incretin hormone with distinct effects