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Three studies comprising 41,984 exposed pregnancies and 136,485 comparator pregnancies found no statistically significant association with cardiac congenital malformations (OR 0.92

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Additional available therapeutic options for more difficult cases of keratosis pilaris include lactic-acid lotions (AmLactin, Lac-Hydrin), alpha-hydroxy-acid lotions (Glytone, glycolic body lotions), urea cream (Carmol 10, Carmol 20, Carmol 40, Urix 40), salicylic acid (Salex lotion), topical tretinoin cream (Retin A), and topical steroid creams (triamcinolone 0.1%)