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Blocks NNMT in fat cells In 3T3-L1 mouse fat cells, 30 M of 5-Amino-1MQ for 24 hours strongly lowered 1-MNA levels direct proof of NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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But it also comes with an important caveat that isnt getting enough attention: this regulatory change is not the same as FDA approval, and how you access these therapies matters just as much as whether you can