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Key Findings: Most common: Nausea (43%), diarrhea (33%), vomiting (21%) Unique to retatrutide: Dysesthesia (20.9% @ 12mg in TRIUMPH-4, 8.8% @ 9mg) Discontinuation rate: 18.2% in TRIUMPH-4, 11.3% in TRIUMPH-1 (general obesity population) compared to semaglutide 6.9%, tirzepatide 6.2% Good news: Most side effects peak during dose escalation and improve significantly after week 16 Management: Slow titration, dietary modifications, and proper timing dramatically reduce severity Understanding the Three Categories of Side Effects 1

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Tirzepatide REPORTS POSTED IN PRODUCT GALLERY Current Batch: 11036-008 Test Date April 2nd, 2026 Purity: 99.903% Net Content: 11.73mg Cap Color: Red Heavy Metal Testing: Lead (Pb): Negative Cadmium (Cd): Negative Arsenic (As): Negative Mercury (Hg): Negative Microbial Sterility Screen: No growth Endotoxin Safety Screen: PASS Current Batch: 11036-007 Test Date: Jan 29th, 2025 Purity: 99.619 Net Content: 10.06 Tirzepatide ( GLP-TZ) Cap Color: Red Endotoxin Test: PASS ( Posted in the Product Gallery) All analyses are conducted for research purposes and performed in duplicate in accordance with USP guidelines