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GLP-1 medications are a high-cost option and must be managed appropriately to ensure patients achieve the desired response

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The pattern of G6PD mutations, whereby null mutations (such as nonsense mutations, frameshifts, or large deletions) are conspicuously absent, is in striking contrast to that seen in other inherited disorders, such as the thalassemias, hemophilia, and muscular dystrophy

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Important note for women of childbearing potential : Tirzepatide can reduce the exposure to oral contraceptives, particularly during initiation and after dose increases

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The appetite suppression from retatrutide must not lead to dangerously low calorie consumption

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