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It's because a medication has a side effect, and like any other side effect, it doesn't affect everyone," Smith-Reed said

In obesity, GLP-1 RAs exert their effects by acting on the hypothalamus and GI system to reduce gastric emptying, enhance satiety and decrease appetite 11

There is no calorie counting and no skipping meals

Participants were 70% female and included those who were obese and had a high rate of prior exposure to advanced therapies, representing a difficult to treat population, according to the researchers