Recent studies have begun to explore these metabolic pathways as potential therapeutic targets
Front Nutr 1:14 Quaife CJ, Findley SD, Erickson JC, Froelick GJ, Kelly EJ, Zambrowicz BP, Palmiter RD (1994) Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia
Together, these results suggest that the dramatically increased EC 50 of vitamin K for VKD carboxylation in DKO cells results from the cells losing the ability to recycle K epo by VKOR, supporting the essential role of VKOR in VKD carboxylation as previously reported 24,25,26
In one study involving men between 60 and 78 years of age, administration of Sermorelin increased both growth hormone and IGF-1 concentrations to levels approaching those typically observed in younger men