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Report any suspected side effects to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk) to help monitor the safety of this medication

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When transitioning from Semaglutide to Tirzepatide, the healthcare provider will determine the appropriate starting dose of Tirzepatide and guide how to discontinue Semaglutide to minimize the risk of adverse effects gradually

For persistent symptoms, consult your healthcare provider about appropriate PPI use and duration