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1 The Joint FAO/WHO Expert Committee on Food Additives has set an acceptable daily intake of 2.5 mg/kg/day for grape-skin-derived ACNs, whereas China has proposed a reference intake of 50 mg/day

Additionally, research has substantiated the significance of Prevotella in the modulation of tear secretion among individuals suffering from DED and demonstrated a positive correlation between the severity of DED and the presence of Prevotella (Zhang et al., 2023a)

In summary, in metformin-treated patients with well-controlled type 2 diabetes, metformin is more effective in glucose-lowering when given before, rather than with, enteral glucose, and this is associated with a greater GLP-1 response

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