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How GLP-1 Medications Differ from Other Weight Loss Drugs: Traditional Weight Loss Medications: Stimulants (phentermine): Increase energy, suppress appetite through adrenaline-like effects Fat blockers (orlistat): Prevent fat absorption in intestines Combination pills (Contrave, Qsymia): Multiple mechanisms, moderate effectiveness These produce 3-9% average weight loss at best

Together, these peptides provide both sustained and pulsatile GH stimulation, creating a balanced effect that supports strength, fat metabolism, recovery, and healthy aging

Patients typically experience dose escalation over 16 weeks, with most clinical benefit accumulating during months 3 through 6 of continuous therapy

(8) Matsui H, et al