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Molecular modeling and laboratory studies conducted over the past two decades suggest that the AEDG sequence can bind to chromatin structures , influencing gene expression associated with aging and cellular regulation

Huang et al., 2025), one examined depression, and the last focused on cognitive performance in older individuals

The neurological definition of sleep has been established since the 195060s to include the main electrophysiological hallmarks of human sleep recorded by polysomnography (PSG), combining electroencephalogram (EEG), electromyogram (EMG of voluntary muscles), electrocardiogram (ECG) and electrooculogram (EOG)