kidney disease and semaglutide Ozempic, Wegovy May Help Reduce Risk semaglutide and kidney disease FLOW

Anand U, Yiangou Y, Akbar A, Quick T, MacQuillan A, Fox M et al (2018) Glucagon-like peptide 1 receptor (GLP-1R) expression by nerve fibres in inflammatory bowel disease and functional effects in cultured neurons

Disclosures Kristin Cecilie Carlsson Petri is employed by and holds stocks in Novo Nordisk A/S

The primary concerns include intensified gastrointestinal side effects (nausea, vomiting, diarrhoea), increased risk of nutritional deficiencies, challenges maintaining adequate protein intake for muscle preservation, and potential dehydration or electrolyte imbalances

6,37,54 Alterations in extracellular adenosine signaling can modulate immune responses, inflammatory processes and immunosuppression