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The aged mice also had compromised learning and memory behaviors and increased anxiety, which suggests that the gut microbiome and the BBB are linked to the deleterious changes in aging brains [96]

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Agonist Development of agonistic analogs of GH-RH The first synthetic analog we developed, [Nle27] GH-RH (129) NH2, replacing Met27 with norleucine (Nle), effectively stimulated GH secretion via intravenous and subcutaneous administration 63,64

Ronald Hugate et al., The effects of intratendinous and retrocalcaneal intrabursal injections of corticosteroid on the biomechanical properties of rabbit Achilles tendons, The Journal of bone and joint surgery