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The EC50 of GLP1 (7-36) is in the expected 2 digits pM range (25-60pM), while its metabolite shows a potency which is 4 logs lower and falls into the low M range

Many, including the supplement Konzier took, feature the plant-derived compound berberine, also called natures Ozempic. Some studies have found berberine can increase GLP-1 production in rats, and potentially drive moderate weight loss in humans, but researchers have called for more conclusive evidence

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