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The IV studies tend to show faster and more pronounced results at the higher achievable concentrations

Registry-only trials were assessed as unclear risk of bias, as critical JBI domains, such as completeness of outcome data, appropriateness of analysis, and selective reporting, cannot be evaluated without peer-reviewed results

For instance, some studies have failed to show any benefit of L-carnitine supplementation on outcomes such as the incidence of heart failure or myocardial reinfarction (CEDIM-2 trial)

The temporal profiling revealed critical insights into the developmental trajectory of hepatocyte and cholangiocyte differentiation, in addition to identifying increased cellular heterogeneity by Day 45