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Recent advances in proteomic technologies have enabled systematic analysis of the expression patterns and regulatory mechanisms of these antioxidant enzymes and markers, providing valuable insights into the complex redox regulation within blood 6

These include: Tier 2 services : Community-based lifestyle interventions Tier 3 services : Specialist multidisciplinary teams for complex obesity Tier 4 services : Bariatric surgery assessment and procedures Referral criteria for these services are outlined in NICE guideline CG189 for obesity management

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