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All participants received treatment for at least 52 weeks, with a maximum treatment duration of 104 weeks or until the study was completed to collect and evaluate major adverse cardiovascular events (MACE)

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[2,6] Also involve them for rapid regain, significant distress, binge patterns, loss-of-control eating, adverse effects particularly persistent gastrointestinal symptoms, or if peri-operative planning is relevant

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2 Introduction/background: history of incretin mimetics medications GIP was the first incretin isolated and characterized in the 1970s though most modern therapies focus on GLP-1 [17]

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