Additional incretin targets in the pipeline include dual co-agonists to glucagon and GLP-1 receptors, triple agonists targeting glucagon, GLP-1 and GIP, novel GLP-1 agonists, oral formulations of GLP-1 agonists, and amylin agonists
The FDA told Business Insider in a statement that it is "actively working" to protect consumers from counterfeit GLP-1s through "public awareness, enforcement actions, and collaboration with other agencies." Last spring, FDA Special Agents worked with the Department of Justice to arrest a woman in New York for selling fake Ozempic and pressed charges against a doctor in Kentucky who was selling "lab research" semaglutide, calling it "Meal Prep" in Venmo payments
This warning is based on findings in rodent studies where these drugs caused thyroid C-cell tumors (medullary thyroid carcinoma) at clinically relevant exposures
(2002), Bupropion SR Enhances Weight Loss: A 48-Week Double-Blind, Placebo- Controlled Trial