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Treatment of hypercholesterolemia rats with Co-Q10 alone or in combination with omega-3 (1,000 mg) regulated cholinergic functioning, reduced brain inflammation and oxidative stress, and increased the functional outcome verified through the histopathological evaluation of brain tissues (Ibrahim Fouad, 2020)

These medications were initially developed and approved for the treatment of type 2 diabetes.6 However, during clinical trials and subsequent use, it became evident that they also led to significant weight loss in many individuals.9 This observation paved the way for some GLP-1 medications to also be approved specifically for weight management in individuals with obesity or overweight who also have weight-related health conditions

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A GFP driven by its own promoter is also present in the construct to allow visualization of viral spreading in the brain structure upon intracranial injection