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The destruction of thyroid follicular cells in Hashimotos thyroiditis is mediated via T cells along with concurrent production of autoantibodies against thyroid-specific proteins including TPO and thyroglobulin

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Key Industry Developments: In October 2025 , Eli Lilly and Company achieved its fourth Phase III success with its oral GLP-1 receptor agonist, orforglipron, in type 2 diabetes trials