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For obesity management, NICE technology appraisals recommend liraglutide 3.0 mg or semaglutide 2.4 mg only as part of a specialist weight management service for adults with a BMI of 35 kg/m (or 32.5 kg/m for people from certain ethnic backgrounds) and at least one weight-related comorbidity
Body composition programmes alongside exercise and nutrition
Its unique mechanism often leads to more significant weight loss compared to single-agonist therapies
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