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He also references concerning studies associating semaglutide usage with up to twice the chance of optic-nerve ischemia as compared to different treatment for diabetes

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Among 47 cases with patients with confirmed MCAS, many of whom had not responded adequately to prior therapies, the case series found that 89% demonstrated clinical benefit with GLP-1RAs across a broad range of symptoms

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People should realize that these are long-term drugs, he said

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