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483,484 The peptide p5RHH has been efficiently used to transfect siRNA and mRNA into human cartilage to reduce chondrocyte apoptosis and prevent cartilage degeneration 485,486,487 as well as into cardiac tissue for treating abdominal aortic aneurysm to reduce the risk of aortic rupture and sudden death in mice

at Camilleri, M., Carlson, P

A systematic review and meta-analysis finds that GLP-1-based treatments drive clinically meaningful weight loss mainly through fat reduction, but experts warn that preserving muscle remains essential for long-term metabolic health

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