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Semaglutide is a member of a class of drugs that has been used for diabetes management for decades, it is a GLP1-RA (glucagon-like peptide 1 receptor agonist)

Augmenting L-cell GLP-1 secretion By doubling meal-related responses of intact, biologically active GLP-1, DPP-4 inhibitors exert profound effects on glycaemic control in patients with type 2 diabetes

Common compounded variations Some formulations pair semaglutide with cyanocobalamin, or vitamin B12, which can reduce injection-site irritation for some patients and may support those who are B12-deficient