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Taking it with meals has shown to decrease its absorption from the gut. Eating certain foods too close to your daily dosage can interfere with how the medication works, including: Soy-based foods or flours, like edamame, tofu, or miso Cottonseed meal Grapefruit or grapefruit juice Walnuts High-calcium foods, like milk, yogurt, or cheese High-fiber foods, like broccoli, cabbage, or kale Fatty, fried, or sugary foods can also slow your metabolism and make it harder to absorb medication

Why Administration Matters Standard oral supplements do not carry this same immediate risk of hypotension because they are processed through the digestive system